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KMID : 1037420080030010048
Journal of Korean Skull Base Society
2008 Volume.3 No. 1 p.48 ~ p.52
Delayed Diagnosis of Thalamic Glioblastoma Presenting as Repeated Intracerebral Hemorrhages
Kim Byeong-Woo

Shim Yu-Shik
Chang Jong-Hee
Ahn Jung-Yong
Abstract
Although rare, neoplasms can be obstructed by intracerebral hemorrhage, delaying histological diagnosis and proper treatment. We report the case of a 30-year-old male presenting with serial intracerebral hemorrhages in the left thalamus. Stereotactic biopsy failed to make histologic diagnosis; open biopsy, two months after the initial hemorrhage, diagnosed glioblastoma. The characteristics of hemorrhage from glioblastoma drawn from our experience and a comprehensive review of the literature include the following: (1) under 14 years of age or old age (2) deep seated supratentorial or posterior fossa location (3) disproportionately diffuse brain edema (4) suspiciously enhancing mass lesion (5) irregular shape and heterogeneous appearance with solid areas of blood, multiple hemorrhage, and a ring-shaped hemorrhage. Direct proof of hemorrhagic origin is necessary for diagnosis and treatment of intracerebral hemorrhage with atypical location, imaging findings, or clinical course.
KEYWORD
Glioblastoma, Intracerebral hemorrhage, Thalamus, Diagnosis
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